Building the Future of Biodefense

Biothreat intelligence to deter and detect natural, accidental, deliberate and novel biological agents.

ADVISORY
PAHO issues updated yellow fever alert; Ecuador reports its 1st case this year
04/25/2025
BrazilBoliviaColombiaPeruEcuador

Recommendation: Yellow fever is endemic in the Amazon regions of South America, though this year, cases have spread outside of traditionally endemic areas. Employees traveling to yellow fever-risk areas in the Americas should consult their healthcare provider at least 10 days before departure about the vaccine. Organizations should provide flexible work schedules ...

Situation: The Pan American Health Organization (PAHO) issued another yellow fever health alert (see PHC alert 3/28). So far this year, 189 confirmed human cases of yellow fever were reported, of which 74 cases were fatal. 4 countries report...

ADVISORY
Western Australia reports 4 invasive meningococcal disease cases in a week
04/25/2025
Australia, Western Australia

Recommendation: Invasive meningococcal disease (IMD) cases have increased in Australia, but annual cases remain below pre-pandemic levels. Organizations with employees traveling to or working in Australia should provide flexible work schedules to allow for vaccination of themselves or family members if not already vaccinated....

Situation: Western Australia reported 4 new IMD cases in the past week, totaling 5 cases in 2025 so far. At least 3 cases were serogroup B. 2 cases were children in the same household, and the other 2 adult cases were unrelated to each other...

ADVISORY
Afghanistan reports concurrent infectious disease outbreaks, including elevated measles activity
04/25/2025
Afghanistan

Recommendation: The civil unrest and limited healthcare infrastructure in Afghanistan will increase the risk of infectious disease outbreaks, including the potential for cross-border spread into neighboring countries. The US State Department lists Afghanistan under a Level 4: Do Not Travel advisory....

Situation: The World Health Organization reported 31,818 suspected measles cases and 208 deaths in Afghanistan so far this year. There has been a steady increase in cases since the beginning of 2025, and cases are higher than the 3-year aver...

WATCH
Rabies-positive bat found by walking path at Rancho Santa Margarita Lake in Orange County, California
04/24/2025
California, Orange County

Recommendation: Human rabies cases are rare but 100% fatal if untreated. Organizations with employees in Orange County, California, should communicate the possible rabies exposure. Organizations should remind employees who work outdoors to avoid interacting with wild animals and seek medical care and contact their local health department if they are bitten or scra...

Situation: Health officials warned the public that a bat discovered at Rancho Santa Margarita Lake in Orange County, California, tested positive for rabies. The bat was found on the ground near a walking path around the lake on 4/17 at about...

ADVISORY
Nevada OSHA to enforce new heat regulation starting on 4/29
04/24/2025
United States of America, Nevada

Recommendation: For informational purposes only. Organizations in Nevada should review their workplace policies to protect workers from heat-related illnesses. This includes reviewing and preparing for compliance with Nevada's new heat regulation before enforcement begins....

Situation: The Nevada Occupational Safety and Health Administration (Nevada OSHA) announced it will fully enforce the state's new Heat Regulation starting 4/29. Businesses with over 10 employees must conduct a job hazard analysis, create a w...

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